Mathias Müller Selected Research

STAT1 Transcription Factor

1/2020	STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity.
1/2018	STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.
8/2013	CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance.
12/2011	Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias.
9/2010	Tyrosine kinase 2 controls IL-1ß production at the translational level.

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Mathias Müller Research Topics

Disease

22	Neoplasms (Cancer) 01/2020 - 05/2002
20	Infections 01/2021 - 12/2002
18	Inflammation (Inflammations) 01/2020 - 06/2006
8	Colitis 04/2021 - 11/2012
5	Septic Shock (Toxic Shock Syndrome) 03/2010 - 05/2003
4	Disease Progression 01/2020 - 03/2010
4	Carcinogenesis 12/2019 - 12/2011
4	Lymphoma (Lymphomas) 01/2019 - 10/2011
4	Shock 12/2014 - 05/2003
3	Sepsis (Septicemia) 12/2014 - 01/2012
3	Virus Diseases (Viral Diseases) 11/2011 - 06/2003
2	Bacterial Infections (Bacterial Infection) 03/2016 - 09/2005
2	Pneumococcal Infections 01/2016 - 08/2013
2	Lung Injury 01/2016 - 09/2015
2	Communicable Diseases (Infectious Diseases) 01/2012 - 12/2005
2	Autoimmune Diseases (Autoimmune Disease) 04/2011 - 10/2008
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2021
1	Hematologic Neoplasms (Hematological Malignancy) 01/2020
1	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 01/2020
1	Liver Diseases (Liver Disease) 12/2019
1	Hepatocellular Carcinoma (Hepatoma) 12/2019
1	Non-alcoholic Fatty Liver Disease 12/2019
1	Glioblastoma (Glioblastoma Multiforme) 09/2019
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 01/2019
1	Genetic Translocation (Chromosomal Translocation) 01/2019
1	Leukemia 01/2018
1	Granuloma 01/2017
1	Hypertrophy 01/2017
1	Tuberous Sclerosis 2 01/2017
1	Sarcoidosis (Schaumann Disease) 01/2017
1	Hypersensitivity (Allergy) 01/2016
1	Anaphylaxis (Anaphylactic Shock) 01/2016
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2016
1	Pancreatic Neoplasms (Pancreatic Cancer) 11/2015
1	Tyrosine Kinase 2 Deficiency 11/2015
1	Pneumonia (Pneumonitis) 09/2015
1	Acute Lung Injury 09/2015
1	Colorectal Neoplasms (Colorectal Cancer) 04/2015
1	Liver Cirrhosis (Hepatic Cirrhosis) 02/2015

Drug/Important Bio-Agent (IBA)

12	Interferon Type IIBA 01/2021 - 05/2003
11	CytokinesIBA 04/2021 - 07/2009
10	Proteins (Proteins, Gene)FDA Link 12/2019 - 05/2002
8	TYK2 Kinase (Tyrosine Kinase 2)IBA 04/2021 - 01/2007
8	InterferonsIBA 01/2018 - 06/2006
7	LipopolysaccharidesIBA 09/2015 - 05/2003
5	STAT1 Transcription FactorIBA 01/2020 - 09/2010
5	Phosphotransferases (Kinase)IBA 11/2019 - 05/2013
5	Dextrans (Dextran)FDA Link 07/2015 - 11/2012
5	sodium sulfate (sodium bisulfate)FDA LinkGeneric 07/2015 - 11/2012
4	Interleukin-10 (Interleukin 10)IBA 12/2014 - 07/2009
3	Transcription Factors (Transcription Factor)IBA 01/2020 - 02/2014
3	Granzymes (Granzyme)IBA 01/2018 - 08/2013
3	Janus KinasesIBA 11/2015 - 01/2007
3	16S Ribosomal RNAIBA 01/2015 - 11/2012
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 05/2013 - 05/2003
2	Biological ProductsIBA 01/2020 - 12/2004
2	Growth Hormone (Somatotropin)IBA 12/2019 - 02/2015
2	Antiviral Agents (Antivirals)IBA 03/2016 - 09/2005
2	Pharmaceutical PreparationsIBA 09/2015 - 08/2010
2	CollagenIBA 02/2015 - 08/2014
2	Biomarkers (Surrogate Marker)IBA 02/2015 - 01/2015
2	Interleukin-27 (Interleukin 27)IBA 12/2014 - 07/2014
2	PerforinIBA 10/2014 - 08/2013
2	FlagellinIBA 05/2014 - 11/2012
2	Protein Kinases (Protein Kinase)IBA 02/2013 - 12/2002
2	thiamine triphosphorate (TTP)IBA 12/2011 - 06/2006
2	TristetraprolinIBA 12/2011 - 06/2006
2	Double-Stranded RNA (RNA, Double Stranded)IBA 11/2011 - 06/2003
2	Dexamethasone (Maxidex)FDA LinkGeneric 04/2011 - 03/2010
1	Protein Isoforms (Isoforms)IBA 01/2020
1	Interleukin-23 (Interleukin 23)IBA 01/2020
1	ruxolitinibIBA 01/2020
1	Janus Kinase InhibitorsIBA 01/2020
1	LipidsIBA 12/2019
1	Anaplastic Lymphoma KinaseIBA 01/2019
1	OligodeoxyribonucleotidesIBA 01/2019
1	Tyrosine (L-Tyrosine)FDA Link 01/2019
1	Aurora KinasesIBA 01/2018
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2017
1	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 04/2016
1	AntigensIBA 01/2016
1	ubenimexIBA 01/2016
1	Methylphenidate (Ritalin)FDA LinkGeneric 01/2016
1	Immunoglobulin E (IgE)IBA 01/2016
1	MicroRNAs (MicroRNA)IBA 11/2015
1	interleukin-22 receptor (IL-22R)IBA 11/2015
1	Interleukin-22 (IL-22)IBA 11/2015
1	Everolimus FDA Link 09/2015
1	Sirolimus (Rapamycin)FDA Link 09/2015
1	MTOR InhibitorsIBA 09/2015
1	dactolisibIBA 09/2015
1	Oleic Acid (Oleate)IBA 09/2015
1	Interferon LambdaIBA 07/2015
1	Calcibiotic Root Canal SealerIBA 04/2015
1	Cholic AcidIBA 02/2015

Therapy/Procedure

6	Therapeutics 09/2019 - 10/2011
2	Transplantation 12/2011 - 10/2008
1	Oral Administration 04/2021
1	Immunotherapy 01/2020
1	Drug Therapy (Chemotherapy) 01/2018